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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-7-30
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pubmed:abstractText |
Replacing heparin with bivalirudin has been beneficial in patients undergoing coronary intervention and coronary artery bypass. The use of this alternative anticoagulant during peripheral bypass operations has not been studied. Concerns over distal thrombosis using this direct thrombin inhibitor (DTI) prompted a single-arm, open-label, pilot prospective trial of bivalirudin in patients undergoing lower extremity bypass to assess perioperative safety and efficacy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1097-6809
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2010 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
369-74
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pubmed:meshHeading |
pubmed-meshheading:20478686-Aged,
pubmed-meshheading:20478686-Ankle Brachial Index,
pubmed-meshheading:20478686-Anticoagulants,
pubmed-meshheading:20478686-Arterial Occlusive Diseases,
pubmed-meshheading:20478686-Blood Loss, Surgical,
pubmed-meshheading:20478686-Hemorrhage,
pubmed-meshheading:20478686-Hirudins,
pubmed-meshheading:20478686-Humans,
pubmed-meshheading:20478686-Infusions, Intravenous,
pubmed-meshheading:20478686-Lower Extremity,
pubmed-meshheading:20478686-Ohio,
pubmed-meshheading:20478686-Peptide Fragments,
pubmed-meshheading:20478686-Pilot Projects,
pubmed-meshheading:20478686-Prospective Studies,
pubmed-meshheading:20478686-Recombinant Proteins,
pubmed-meshheading:20478686-Reoperation,
pubmed-meshheading:20478686-Saphenous Vein,
pubmed-meshheading:20478686-Thrombin,
pubmed-meshheading:20478686-Thrombosis,
pubmed-meshheading:20478686-Time Factors,
pubmed-meshheading:20478686-Treatment Outcome,
pubmed-meshheading:20478686-Vascular Patency,
pubmed-meshheading:20478686-Vascular Surgical Procedures
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pubmed:year |
2010
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pubmed:articleTitle |
A pilot, prospective evaluation of a direct thrombin inhibitor, bivalirudin (Angiomax), in patients undergoing lower extremity bypass.
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pubmed:affiliation |
Department of Vascular Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA. kashyav@ccf.org
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase III
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