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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-7-12
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pubmed:abstractText |
Several biologic mediators and genetic predisposing factors may contribute to the development of peripheral arterial disease (PAD). The eNOS gene, encoding for endothelial nitric oxide synthase, has been proposed as a candidate gene in the predisposition to the disease. In this study, we evaluated the role of eNOS-786T>C, -894G>T and 4a/4b polymorphisms as markers of PAD per se and in the presence of the ACE D allele in patients previously investigated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1097-6809
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2010 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-102.e1
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pubmed:meshHeading |
pubmed-meshheading:20478683-Aged,
pubmed-meshheading:20478683-Case-Control Studies,
pubmed-meshheading:20478683-Chi-Square Distribution,
pubmed-meshheading:20478683-Female,
pubmed-meshheading:20478683-Gene Frequency,
pubmed-meshheading:20478683-Genetic Predisposition to Disease,
pubmed-meshheading:20478683-Haplotypes,
pubmed-meshheading:20478683-Humans,
pubmed-meshheading:20478683-Logistic Models,
pubmed-meshheading:20478683-Male,
pubmed-meshheading:20478683-Nitric Oxide Synthase Type III,
pubmed-meshheading:20478683-Odds Ratio,
pubmed-meshheading:20478683-Peptidyl-Dipeptidase A,
pubmed-meshheading:20478683-Peripheral Vascular Diseases,
pubmed-meshheading:20478683-Polymorphism, Genetic,
pubmed-meshheading:20478683-Retrospective Studies,
pubmed-meshheading:20478683-Risk Assessment,
pubmed-meshheading:20478683-Risk Factors,
pubmed-meshheading:20478683-Smoking
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pubmed:year |
2010
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pubmed:articleTitle |
eNOS and ACE genes influence peripheral arterial disease predisposition in smokers.
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pubmed:affiliation |
Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
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pubmed:publicationType |
Journal Article
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