| pubmed-article:20478633 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20478633 | lifeskim:mentions | umls-concept:C0025611 | lld:lifeskim |
| pubmed-article:20478633 | lifeskim:mentions | umls-concept:C0680174 | lld:lifeskim |
| pubmed-article:20478633 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
| pubmed-article:20478633 | lifeskim:mentions | umls-concept:C0439857 | lld:lifeskim |
| pubmed-article:20478633 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:20478633 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:20478633 | lifeskim:mentions | umls-concept:C0439611 | lld:lifeskim |
| pubmed-article:20478633 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:20478633 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:20478633 | pubmed:dateCreated | 2010-7-12 | lld:pubmed |
| pubmed-article:20478633 | pubmed:abstractText | Research into the biological processes that increase susceptibility to methamphetamine dependence has been conducted primarily in Asian populations. Using a case-control design this study's purpose was to explore, among a population of methamphetamine-dependent Caucasians, six putative single nucleotide polymorphisms previously found to be associated with methamphetamine dependence in Asian populations. A total of 193 non-psychotic males (117 methamphetamine-dependent and 76 controls) were genotyped for variants located in six genes (AKT1, ARRB2, BDNF, COMT, GSTP1, OPRM1). Genotypic and allelic frequencies, odds ratios, and 95% confidence intervals were calculated. None of the putative gene associations was significantly replicated in our sample of Caucasian men. Effect size comparisons suggest a trend toward allelic divergence for arrestin beta 2 (ARRB2) and glutathione S-transferase P1 (GSTP1) and allelic convergence for brain-derived neurotrophic factor (BDNF). Results provide preliminary support for further exploration and validation of candidate single nucleotide polymorphisms (SNPs) for methamphetamine (METH) dependence reported among Asian populations across other ethnic/ancestral groups. | lld:pubmed |
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| pubmed-article:20478633 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:20478633 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:20478633 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20478633 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:20478633 | pubmed:issn | 0165-1781 | lld:pubmed |
| pubmed-article:20478633 | pubmed:author | pubmed-author:HNRC Group | lld:pubmed |
| pubmed-article:20478633 | pubmed:author | pubmed-author:TsuangMing... | lld:pubmed |
| pubmed-article:20478633 | pubmed:author | pubmed-author:EverallIan... | lld:pubmed |
| pubmed-article:20478633 | pubmed:author | pubmed-author:GlattStephen... | lld:pubmed |
| pubmed-article:20478633 | pubmed:author | pubmed-author:GrantIgorI | lld:pubmed |
| pubmed-article:20478633 | pubmed:author | pubmed-author:ChernerMarian... | lld:pubmed |
| pubmed-article:20478633 | pubmed:author | pubmed-author:AtkinsonJ... | lld:pubmed |
| pubmed-article:20478633 | pubmed:author | pubmed-author:BousmanChad... | lld:pubmed |
| pubmed-article:20478633 | pubmed:copyrightInfo | Copyright 2009 Elsevier Ireland Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:20478633 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:20478633 | pubmed:day | 30 | lld:pubmed |
| pubmed-article:20478633 | pubmed:volume | 178 | lld:pubmed |
| pubmed-article:20478633 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20478633 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20478633 | pubmed:pagination | 295-8 | lld:pubmed |
| pubmed-article:20478633 | pubmed:dateRevised | 2011-8-2 | lld:pubmed |
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| pubmed-article:20478633 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20478633 | pubmed:articleTitle | Preliminary evidence of ethnic divergence in associations of putative genetic variants for methamphetamine dependence. | lld:pubmed |
| pubmed-article:20478633 | pubmed:affiliation | Department of Psychiatry, University of California San Diego, La Jolla, CA 92103, USA. cbousman@ucsd.edu | lld:pubmed |
| pubmed-article:20478633 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20478633 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:20478633 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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