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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1991-7-18
|
| pubmed:abstractText |
The discovery of idiotypes by Oudin and Kunkel, followed by the idiotype network theory by Jerne have opened a new field of investigation of the humoral immune response and of its regulation. The presence of anti-idiotypes behaving like "internal images" and the ability of anti-idiotypes to modulate the immune response in animals lead the way to new therapeutic regimens in very various fields such as auto-immune diseases or vaccinations. However, many theoretical as well as practical problems need to be solved before the actual use of such reagents in clinical medicine.
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
F
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0035-2640
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
21
|
| pubmed:volume |
41
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
801-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1991
|
| pubmed:articleTitle |
[Anti-idiotype antibodies].
|
| pubmed:affiliation |
Service de néphrologie et unité INSERM U 28, hôpital Broussais, Paris.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|