Linked Life Data

20477018

Source:http://linkedlifedata.com/resource/pubmed/id/20477018

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-5-18
pubmed:abstractText
Evaluation of: He LZ, Crocker A, Lee J et al. Antigenic targeting of the human mannose receptor induces tumor immunity. J. Immunol. 178(10), 6259-6267 (2007). Induction of adaptive immune response requires, in most cases, internalization of the antigen by professional antigen-presenting cells. Various endocytic receptors may mediate such interaction. However, little is known regarding the exact participation of such receptors in the context of immune response in vivo. This paper evaluates a recent work that utilizes one such molecule, the human CD206, transgenically incorporated into mouse, in order to establish its role in immune response. Such a study benefits from the fact that the function of the human form of the receptor is elaborated and thus would help to define new targets for future vaccine strategies.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Sep
pubmed:issn
1744-8409
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
677-81
pubmed:year
2007
pubmed:articleTitle
Human mannose receptor (CD206) in immune response: novel insights into vaccination strategies using a humanized mouse model.
pubmed:affiliation
Unité 872, Institut National de la Santé et de la Recherche Médicale, F-75006 Paris, France. surya.dasgupta@crc.jussieu.fr
pubmed:publicationType
Journal Article, Comment