Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2010-6-7
pubmed:abstractText
This study examined whether maternal background and perinatal factors were associated with the risk of cow's milk allergy (CMA) in infants up to 2 years of age in a nested case-control study. All children born in 1996-2004 in Finland and diagnosed with CMA by 2006 were identified (n = 16,237). For each case, one matched control was selected. Information on maternal and perinatal factors was derived from the Medical Birth Register. The associations were analyzed by conditional logistic regression. Cesarean section (adjusted odds ratio (OR) = 1.18, 95% confidence interval (CI): 1.10, 1.27) and high maternal age (> or =35 years; adjusted OR = 1.23, 95% CI: 1.11, 1.36) were associated with increased risk, whereas low maternal socioeconomic status (adjusted OR = 0.65, 95% CI: 0.59, 0.71), smoking (adjusted OR = 0.72, 95% CI: 0.67, 0.79), high number of previous deliveries (> or =5; adjusted OR = 0.71, 95% CI: 0.59, 0.86), and multiple pregnancy (adjusted OR = 0.70, 95% CI: 0.60, 0.82) were associated with decreased risk of CMA. In conclusion, maternal background and perinatal factors may play a role in the development of CMA, but further research is needed to clarify these associations and the underpinning biologic mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1476-6256
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
171
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1310-6
pubmed:meshHeading
pubmed-meshheading:20472571-Adolescent, pubmed-meshheading:20472571-Adult, pubmed-meshheading:20472571-Animals, pubmed-meshheading:20472571-Case-Control Studies, pubmed-meshheading:20472571-Cattle, pubmed-meshheading:20472571-Cesarean Section, pubmed-meshheading:20472571-Confidence Intervals, pubmed-meshheading:20472571-Female, pubmed-meshheading:20472571-Finland, pubmed-meshheading:20472571-Food Hypersensitivity, pubmed-meshheading:20472571-Gestational Age, pubmed-meshheading:20472571-Humans, pubmed-meshheading:20472571-Infant, pubmed-meshheading:20472571-Logistic Models, pubmed-meshheading:20472571-Male, pubmed-meshheading:20472571-Maternal Age, pubmed-meshheading:20472571-Middle Aged, pubmed-meshheading:20472571-Milk, pubmed-meshheading:20472571-Mothers, pubmed-meshheading:20472571-Odds Ratio, pubmed-meshheading:20472571-Parity, pubmed-meshheading:20472571-Pregnancy, pubmed-meshheading:20472571-Pregnancy, Multiple, pubmed-meshheading:20472571-Risk Factors, pubmed-meshheading:20472571-Sex Factors, pubmed-meshheading:20472571-Smoking, pubmed-meshheading:20472571-Socioeconomic Factors, pubmed-meshheading:20472571-Young Adult
pubmed:year
2010
pubmed:articleTitle
Maternal and perinatal characteristics and the risk of cow's milk allergy in infants up to 2 years of age: a case-control study nested in the Finnish population.
pubmed:affiliation
Department of Health, Functional Capacity and Welfare, National Institute for Health and Welfare, Helsinki, Finland. johanna.metsala@thl.fi
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't