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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
2010-7-12
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pubmed:abstractText |
The clinical relevance of frequent methylation of CpG islands of key cancer genes in breast cancer is being increasingly recognized. Our study aimed to evaluate the promoter methylation status of DNA repair genes-BRCA1MGMT and GSTP1 in tumor and circulating DNA of invasive ductal breast carcinoma patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BRCA1 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Modification Methylases,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Repair Enzymes,
http://linkedlifedata.com/resource/pubmed/chemical/GSTP1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione S-Transferase pi,
http://linkedlifedata.com/resource/pubmed/chemical/MGMT protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
17
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
83-91
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pubmed:meshHeading |
pubmed-meshheading:20470789-Adult,
pubmed-meshheading:20470789-Aged,
pubmed-meshheading:20470789-Aged, 80 and over,
pubmed-meshheading:20470789-BRCA1 Protein,
pubmed-meshheading:20470789-Breast Neoplasms,
pubmed-meshheading:20470789-Carcinoma, Ductal, Breast,
pubmed-meshheading:20470789-Case-Control Studies,
pubmed-meshheading:20470789-DNA, Neoplasm,
pubmed-meshheading:20470789-DNA Methylation,
pubmed-meshheading:20470789-DNA Modification Methylases,
pubmed-meshheading:20470789-DNA Repair Enzymes,
pubmed-meshheading:20470789-Female,
pubmed-meshheading:20470789-Follow-Up Studies,
pubmed-meshheading:20470789-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20470789-Gene Silencing,
pubmed-meshheading:20470789-Glutathione S-Transferase pi,
pubmed-meshheading:20470789-Humans,
pubmed-meshheading:20470789-Middle Aged,
pubmed-meshheading:20470789-Neoplasm Recurrence, Local,
pubmed-meshheading:20470789-Polymerase Chain Reaction,
pubmed-meshheading:20470789-Prognosis,
pubmed-meshheading:20470789-Promoter Regions, Genetic,
pubmed-meshheading:20470789-Prospective Studies,
pubmed-meshheading:20470789-Tumor Suppressor Proteins,
pubmed-meshheading:20470789-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Clinical significance of promoter hypermethylation of DNA repair genes in tumor and serum DNA in invasive ductal breast carcinoma patients.
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pubmed:affiliation |
Department of Biochemistry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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