Source:http://linkedlifedata.com/resource/pubmed/id/20466664
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2010-9-23
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pubmed:abstractText |
Non-diabetic forms of nephropathy commonly lead to end-stage renal disease (non-DM ESRD). Previous studies have demonstrated that African Americans are more susceptible to non-DM ESRD compared to other ethnic groups, and this risk has a strong genetic component. A genome-wide scan for ESRD in African American families enriched for non-DM ESRD showed evidence for linkage in chromosome 13q33.3, and a candidate gene in this region, klotho, was selected for a detailed analysis in a follow-up case-control association study.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1460-2385
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3348-55
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pubmed:dateRevised |
2011-10-3
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pubmed:meshHeading |
pubmed-meshheading:20466664-Adult,
pubmed-meshheading:20466664-African Americans,
pubmed-meshheading:20466664-Aged,
pubmed-meshheading:20466664-Female,
pubmed-meshheading:20466664-Glucuronidase,
pubmed-meshheading:20466664-Haplotypes,
pubmed-meshheading:20466664-Humans,
pubmed-meshheading:20466664-Kidney Failure, Chronic,
pubmed-meshheading:20466664-Male,
pubmed-meshheading:20466664-Middle Aged,
pubmed-meshheading:20466664-Polymorphism, Single Nucleotide
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pubmed:year |
2010
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pubmed:articleTitle |
Association of polymorphisms in the klotho gene with severity of non-diabetic ESRD in African Americans.
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pubmed:affiliation |
Department of Biochemistry, Center for HumanGenomics, Wake Forest University School of Medicine, Winston-Salem, NC USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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