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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-8-2
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pubmed:abstractText |
Low levels of high-density lipoprotein cholesterol (HDL-C) are a risk factor for coronary artery disease (CAD) and possibly for deep venous thrombosis (DVT). Endothelial lipase is involved in HDL-C metabolism. Common variants in the endothelial lipase gene (LIPG) have been reported to be associated with HDL-C levels and atherothrombosis, but these findings were not consistent. We determined whether five tagging single nucleotide polymorphisms (SNP) in LIPG were associated with lipid parameters, the risk of CAD and the risk of DVT.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1879-1484
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pubmed:author |
pubmed-author:BoekholdtS MatthijsSM,
pubmed-author:CohnDanny MDM,
pubmed-author:Dallinga-ThieGeesje MGM,
pubmed-author:KamphuisenPieter WPW,
pubmed-author:KasteleinJohn J PJJ,
pubmed-author:KhawKay-TeeKT,
pubmed-author:PrinsHester MHM,
pubmed-author:RickettsSally LSL,
pubmed-author:SandhuManjinder SMS,
pubmed-author:VergeerMennoM,
pubmed-author:WarehamNicholas JNJ
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
211
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
558-64
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pubmed:meshHeading |
pubmed-meshheading:20466371-Aged,
pubmed-meshheading:20466371-Alleles,
pubmed-meshheading:20466371-Cholesterol, HDL,
pubmed-meshheading:20466371-Coronary Artery Disease,
pubmed-meshheading:20466371-Female,
pubmed-meshheading:20466371-Genetic Variation,
pubmed-meshheading:20466371-Genotype,
pubmed-meshheading:20466371-Humans,
pubmed-meshheading:20466371-Lipase,
pubmed-meshheading:20466371-Male,
pubmed-meshheading:20466371-Middle Aged,
pubmed-meshheading:20466371-Polymorphism, Single Nucleotide,
pubmed-meshheading:20466371-Risk,
pubmed-meshheading:20466371-Thrombosis,
pubmed-meshheading:20466371-Venous Thrombosis
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pubmed:year |
2010
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pubmed:articleTitle |
Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT.
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pubmed:affiliation |
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands. m.vergeer@amc.uva.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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