Linked Life Data

20463109

Source:http://linkedlifedata.com/resource/pubmed/id/20463109

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-5-13
pubmed:abstractText
The authors present a literature review exploring the possible association between APOE epsilon4 and cognitive dysfunction in multiple sclerosis. Differences in magnetic resonance (MR)-elicited brain pathology between epsilon4+ and epsilon4- multiple sclerosis patients were also considered. Overall, the cognitive literature suggests the likelihood of a gene-cognition relationship. A less certain picture pertains to the gene-MR data. Methodological considerations, however, leave many questions unanswered and the conclusions should be viewed in this light. No study has yet combined neuropsychological inquiry, brain imaging, and genetic determination, an approach that has the potential to pull together various pieces of the puzzle.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1545-7222
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
155-65
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
APOE epsilon4 and cognitive dysfunction in multiple sclerosis: a review.
pubmed:affiliation
Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada M4N 3M5. omar.ghaffar@utoronto.ca
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't