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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-6-4
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pubmed:abstractText |
An inappropriate activation of the mTOR pathway was demonstrated in the autosomal dominant (AD) form of polycystic kidney disease (PKD). To date it is unclear whether the mTOR pathway is activated in autosomal-recessive (AR) PKD, a cystic disease which occurs in childhood. The purpose of the present study was to evaluate the mTOR pathway in AR PKD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0143
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129-38
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20460933-Adolescent,
pubmed-meshheading:20460933-Animals,
pubmed-meshheading:20460933-Bile Ducts,
pubmed-meshheading:20460933-Child,
pubmed-meshheading:20460933-Female,
pubmed-meshheading:20460933-Humans,
pubmed-meshheading:20460933-Immunohistochemistry,
pubmed-meshheading:20460933-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:20460933-Kidney,
pubmed-meshheading:20460933-Kidney Transplantation,
pubmed-meshheading:20460933-Liver,
pubmed-meshheading:20460933-Liver Transplantation,
pubmed-meshheading:20460933-Male,
pubmed-meshheading:20460933-Polycystic Kidney, Autosomal Recessive,
pubmed-meshheading:20460933-Protein-Serine-Threonine Kinases,
pubmed-meshheading:20460933-TOR Serine-Threonine Kinases
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pubmed:year |
2010
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pubmed:articleTitle |
The mTOR pathway is activated in human autosomal-recessive polycystic kidney disease.
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pubmed:affiliation |
Institute of Pathology and Neuropathology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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