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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-5-12
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pubmed:abstractText |
Activation of Notch signalling results in hyperplasia and tumorigenesis in murine mammary epithelium. However, there is little information regarding the expression of Notch1 in premalignant lesions and early breast cancer. We investigated expression of Notch1 in breast cancer development and its association with molecular subtypes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1365-2559
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pubmed:author |
pubmed-author:CreaPaulP,
pubmed-author:HamiltonAnneA,
pubmed-author:Lopez-KnowlesElenaE,
pubmed-author:McLeodDuncanD,
pubmed-author:McNeilCatriona MCM,
pubmed-author:MillarEwan K AEK,
pubmed-author:MoreyAdrienne LAL,
pubmed-author:MurphyNiamh CNC,
pubmed-author:MusgroveElizabeth AEA,
pubmed-author:O'TooleSandra ASA,
pubmed-author:OakesSamantha RSR,
pubmed-author:OrmandyChristopher JCJ,
pubmed-author:PineseMarkM,
pubmed-author:QiuMin RuMR,
pubmed-author:Soon LeeCheokC,
pubmed-author:SpillaneAndrewA,
pubmed-author:SutherlandRobert LRL,
pubmed-author:ZardawiIbrahimI,
pubmed-author:ZardawiSarah JSJ
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pubmed:issnType |
Electronic
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
286-96
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20459529-Adult,
pubmed-meshheading:20459529-Aged,
pubmed-meshheading:20459529-Aged, 80 and over,
pubmed-meshheading:20459529-Animals,
pubmed-meshheading:20459529-Breast Neoplasms,
pubmed-meshheading:20459529-Carcinoma, Ductal, Breast,
pubmed-meshheading:20459529-Disease Progression,
pubmed-meshheading:20459529-Female,
pubmed-meshheading:20459529-Humans,
pubmed-meshheading:20459529-Immunohistochemistry,
pubmed-meshheading:20459529-Kaplan-Meier Estimate,
pubmed-meshheading:20459529-Mice,
pubmed-meshheading:20459529-Middle Aged,
pubmed-meshheading:20459529-Phenotype,
pubmed-meshheading:20459529-Receptor, Notch1,
pubmed-meshheading:20459529-Receptor, erbB-2,
pubmed-meshheading:20459529-Signal Transduction,
pubmed-meshheading:20459529-Tissue Array Analysis,
pubmed-meshheading:20459529-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
High Notch1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype.
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pubmed:affiliation |
Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Darlinghurst, NSW, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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