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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1991-7-15
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pubmed:abstractText |
Cholescintigrams were performed in 158 patients suspected of having acute cholecystitis after administration of 185 Mbq (5 mCi) of 99mTc-mebrofenin or disofenin. Morphine sulfate, 0.04 mg/kg was given intravenously if there was nonvisualization of the gallbladder at 40-60 min provided that radiotracer was seen within the small bowel. Acute cholecystitis was deemed present if there was nonvisualization of the gallbladder 30 min post-morphine administration; no cystic duct obstruction was present if the gallbladder was demonstrated pre- or post-morphine administration. A final diagnosis was estimated in 51 postoperative patients histologically, the remainder having their final diagnosis gleaned from their medical records. The sensitivity, specificity, positive and negative predictive value of morphine-augmented cholescintigraphy in detecting acute cholecystitis was 94.6, 99.1, 97.2, and 98.3%, respectively. These findings indicate that morphine-augmented cholescintigraphy detects acute cholecystitis with as high a degree of accuracy as conventional hepatobiliary scintigraphy, yet requires only 1.5 hr to establish the diagnosis.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Imino Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Morphine,
http://linkedlifedata.com/resource/pubmed/chemical/Organotechnetium Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium Tc 99m Disofenin,
http://linkedlifedata.com/resource/pubmed/chemical/technetium Tc 99m mebrofenin
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0161-5505
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1231-3
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2045939-Acute Disease,
pubmed-meshheading:2045939-Adult,
pubmed-meshheading:2045939-Aged,
pubmed-meshheading:2045939-Aged, 80 and over,
pubmed-meshheading:2045939-Cholecystitis,
pubmed-meshheading:2045939-Female,
pubmed-meshheading:2045939-Humans,
pubmed-meshheading:2045939-Imino Acids,
pubmed-meshheading:2045939-Injections, Intravenous,
pubmed-meshheading:2045939-Male,
pubmed-meshheading:2045939-Middle Aged,
pubmed-meshheading:2045939-Morphine,
pubmed-meshheading:2045939-Organotechnetium Compounds,
pubmed-meshheading:2045939-Retrospective Studies,
pubmed-meshheading:2045939-Sensitivity and Specificity,
pubmed-meshheading:2045939-Technetium Tc 99m Disofenin
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pubmed:year |
1991
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pubmed:articleTitle |
Morphine-augmented cholescintigraphy: its efficacy in detecting acute cholecystitis.
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pubmed:affiliation |
Department of Nuclear Medicine, William Beaumont Hospital, Royal Oak, Michigan 48073.
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pubmed:publicationType |
Journal Article
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