Source:http://linkedlifedata.com/resource/pubmed/id/20455662
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-5-11
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pubmed:abstractText |
Two unique, formerly unrecorded sellar neoplasms were observed in two women of 60 and 63 years of age. One lesion consisted of small epithelial cells and the other was a large-cell oncocytic tumor, yet they had the same simple cytoplasmic organization with dominance of polyribosomes and a sprinkle of glycogen. Striking markers shared by the neoplasms: (1) network of typical pituitary follicles, and (2) unexpected similarity to fetal human pituitary tissue at different gestational ages of 6 and 10-12 weeks. The latter showed appreciable endocrine differentiation. The assumed parent cell is the folliculo-stellate cell as pluripotent adult stem cell.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1521-0758
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-9
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pubmed:meshHeading |
pubmed-meshheading:20455662-Female,
pubmed-meshheading:20455662-Humans,
pubmed-meshheading:20455662-Microscopy, Electron, Transmission,
pubmed-meshheading:20455662-Middle Aged,
pubmed-meshheading:20455662-Neoplasm Recurrence, Local,
pubmed-meshheading:20455662-Neoplastic Stem Cells,
pubmed-meshheading:20455662-Pituitary Gland, Anterior,
pubmed-meshheading:20455662-Pituitary Neoplasms,
pubmed-meshheading:20455662-Pluripotent Stem Cells,
pubmed-meshheading:20455662-Polyribosomes,
pubmed-meshheading:20455662-Sella Turcica,
pubmed-meshheading:20455662-Tumor Markers, Biological
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pubmed:year |
2010
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pubmed:articleTitle |
Folliculo-stellate cells of the human pituitary as adult stem cells: examples of their neoplastic potential.
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pubmed:affiliation |
Department of Laboratory Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. kovacsk@smh.ca
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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