Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-5-10
pubmed:abstractText
Recent years have seen the emergence of microelectrode arrays and optical methods allowing simultaneous recording of spiking activity from populations of neurons in various parts of the nervous system. The analysis of multiple neural spike train data could benefit significantly from existing methods for multivariate time-series analysis which have proven to be very powerful in the modeling and analysis of continuous neural signals like EEG signals. However, those methods have not generally been well adapted to point processes. Here, we use our recent results on correlation distortions in multivariate Linear-Nonlinear-Poisson spiking neuron models to derive generalized Yule-Walker-type equations for fitting ''hidden" Multivariate Autoregressive models. We use this new framework to perform Granger causality analysis in order to extract the directed information flow pattern in networks of simulated spiking neurons. We discuss the relative merits and limitations of the new method.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-10638818, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-11110130, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-11255567, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-11508777, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-11752471, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-12396564, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-12634276, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-12750897, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-14511525, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-15218350, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-15356183, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-15456829, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-15992486, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-16140522, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-16278654, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-16289760, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-16378515, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-16761264, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-16927098, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-18073408, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-18244602, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-18632888, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-18650810, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-19137420, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-19191596, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-19196233, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-19670479, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-2340346, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-2996632, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-3196770, http://linkedlifedata.com/resource/pubmed/commentcorrection/20454705-3801543
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1687-5273
pubmed:author
pubmed:issnType
Electronic
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
752428
pubmed:dateRevised
2010-9-30
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Multivariate autoregressive modeling and granger causality analysis of multiple spike trains.
pubmed:affiliation
Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, 32000 Haifa, Israel.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't