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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-5-10
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pubmed:abstractText |
We have previously demonstrated that induction of profound hypothermia improves long-term survival in animal models of complex injuries/lethal hemorrhage. However, the precise mechanisms have not been well defined. The aim of this high-throughput study was to investigate the impact of profound hypothermia on gene expression profiles.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1529-8809
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1084-98
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pubmed:dateRevised |
2010-7-16
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pubmed:meshHeading |
pubmed-meshheading:20453763-Acidosis, Lactic,
pubmed-meshheading:20453763-Analysis of Variance,
pubmed-meshheading:20453763-Animals,
pubmed-meshheading:20453763-Apoptosis,
pubmed-meshheading:20453763-Cardiopulmonary Bypass,
pubmed-meshheading:20453763-Disease Models, Animal,
pubmed-meshheading:20453763-Gene Expression Profiling,
pubmed-meshheading:20453763-Gene Expression Regulation,
pubmed-meshheading:20453763-Hypothermia, Induced,
pubmed-meshheading:20453763-Male,
pubmed-meshheading:20453763-Metabolic Networks and Pathways,
pubmed-meshheading:20453763-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20453763-Oxygen Consumption,
pubmed-meshheading:20453763-Random Allocation,
pubmed-meshheading:20453763-Rats,
pubmed-meshheading:20453763-Rats, Inbred WKY,
pubmed-meshheading:20453763-Resuscitation,
pubmed-meshheading:20453763-Shock, Hemorrhagic,
pubmed-meshheading:20453763-Survival Rate,
pubmed-meshheading:20453763-Transcription, Genetic,
pubmed-meshheading:20453763-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Alterations in gene expression after induction of profound hypothermia for the treatment of lethal hemorrhage.
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pubmed:affiliation |
Division of Trauma, Department of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts 02114, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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