|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0012133,
umls-concept:C0023516,
umls-concept:C0041904,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0225336,
umls-concept:C0663655,
umls-concept:C1334146,
umls-concept:C1366562,
umls-concept:C1704675,
umls-concept:C1706439
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2010-6-18
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|
pubmed:abstractText |
Abacavir and didanosine are nucleoside reverse transcriptase inhibitors (NRTI) widely used in therapy for HIV-infection but which have been linked to cardiovascular complications. The objective of this study was to analyze the effects of clinically relevant doses of abacavir and didanosine on human leukocyte-endothelium interactions and to compare them with those of other NRTIs.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1473-5571
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
1
|
|
pubmed:volume |
24
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1259-66
|
|
pubmed:meshHeading |
pubmed-meshheading:20453628-Analysis of Variance,
pubmed-meshheading:20453628-Cardiovascular Diseases,
pubmed-meshheading:20453628-Cell Adhesion Molecules,
pubmed-meshheading:20453628-Cell Communication,
pubmed-meshheading:20453628-Didanosine,
pubmed-meshheading:20453628-Dideoxynucleosides,
pubmed-meshheading:20453628-Endothelial Cells,
pubmed-meshheading:20453628-Endothelium, Vascular,
pubmed-meshheading:20453628-Humans,
pubmed-meshheading:20453628-Leukocytes,
pubmed-meshheading:20453628-Macrophage-1 Antigen,
pubmed-meshheading:20453628-Reverse Transcriptase Inhibitors,
pubmed-meshheading:20453628-Up-Regulation
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Abacavir and didanosine induce the interaction between human leukocytes and endothelial cells through Mac-1 upregulation.
|
|
pubmed:affiliation |
Departamento de Farmacología and CIBERehd, Universidad de Valencia, Spain.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
