20451184

Source:http://linkedlifedata.com/resource/pubmed/id/20451184

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007589, umls-concept:C0018270, umls-concept:C0032854, umls-concept:C0043210, umls-concept:C0205065, umls-concept:C0205216, umls-concept:C0949385, umls-concept:C1274040, umls-concept:C1511938, umls-concept:C1561558, umls-concept:C1880177, umls-concept:C1882417, umls-concept:C2347957
pubmed:issue	6
pubmed:dateCreated	2010-10-27
pubmed:abstractText	The growth differential factor-9 (GDF-9) gene, an oocyte-specific factor, was screened in 106 Chinese women with diminished ovarian reserve (DOR), and three single-nucleotide polymorphisms, c.G169A, c.C447T and c.G546A, were detected. We found GDF-9 c.G546A, but not c.G169A or c.C447T, to be correlated with the poor ovarian stimulation and in vitro fertilization outcomes in women with DOR.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0372772
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Growth Differentiation Factor 9
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	1556-5653
pubmed:author	pubmed-author:DongMin-YueMY, pubmed-author:HuangHe-FengHF, pubmed-author:LeungPeter C KPC, pubmed-author:ShengJian-ZhongJZ, pubmed-author:WangTing-TingTT, pubmed-author:WuYan-TingYT
pubmed:copyrightInfo	Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
pubmed:issnType	Electronic
pubmed:volume	94
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2490-2
pubmed:meshHeading	pubmed-meshheading:20451184-Adult, pubmed-meshheading:20451184-Cell Count, pubmed-meshheading:20451184-Female, pubmed-meshheading:20451184-Fertilization in Vitro, pubmed-meshheading:20451184-Genetic Predisposition to Disease, pubmed-meshheading:20451184-Growth Differentiation Factor 9, pubmed-meshheading:20451184-Humans, pubmed-meshheading:20451184-Infertility, Female, pubmed-meshheading:20451184-Mutation, Missense, pubmed-meshheading:20451184-Ovary, pubmed-meshheading:20451184-Ovulation Induction, pubmed-meshheading:20451184-Polymorphism, Single Nucleotide, pubmed-meshheading:20451184-Pregnancy, pubmed-meshheading:20451184-Pregnancy Rate, pubmed-meshheading:20451184-Primary Ovarian Insufficiency, pubmed-meshheading:20451184-Prognosis, pubmed-meshheading:20451184-Risk Factors, pubmed-meshheading:20451184-Treatment Outcome
pubmed:year	2010
pubmed:articleTitle	G546A polymorphism of growth differentiation factor-9 contributes to the poor outcome of ovarian stimulation in women with diminished ovarian reserve.
pubmed:affiliation	Department of Reproductive Endocrinology, Zhejiang Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.
pubmed:publicationType	Journal Article, Controlled Clinical Trial, Research Support, Non-U.S. Gov't