Source:http://linkedlifedata.com/resource/pubmed/id/20447775
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
2010-10-5
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pubmed:abstractText |
Haemophilus parasuis is the etiologic agent of Glässer's disease in pigs and a colonizer of the upper respiratory tract of healthy pigs. A good balance between colonization and immunity is important to avoid a disease outbreak. This work studied the colonization of H. parasuis in healthy piglets coming from vaccinated and non-vaccinated sows. Piglets from vaccinated sows had higher IgG levels at early time points and subsequently were colonized later and to a lower degree than piglets from non-vaccinated ones. The variability of H. parasuis isolates was investigated by 2 genotyping methods: enterobacterial repetitive intergenic consensus (ERIC)-PCR and multilocus sequence typing (MLST). A high turnover of strains was found in both groups of piglets, with few strains found on more than one sampling occasion. We found a higher number of H. parasuis strains (16 strains) within a given farm than previously thought. Overall, more H. parasuis diversity was found in piglets from non-vaccinated sows than in those from vaccinated sows. These results indicate that vaccination of sows in a farm delays the colonization of piglets and reduces the carriage and heterogeneity of H. parasuis strains.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1873-2542
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
26
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
315-20
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pubmed:meshHeading |
pubmed-meshheading:20447775-Animals,
pubmed-meshheading:20447775-Animals, Newborn,
pubmed-meshheading:20447775-Antibodies, Bacterial,
pubmed-meshheading:20447775-Bacterial Vaccines,
pubmed-meshheading:20447775-Cluster Analysis,
pubmed-meshheading:20447775-DNA Fingerprinting,
pubmed-meshheading:20447775-Female,
pubmed-meshheading:20447775-Genetic Variation,
pubmed-meshheading:20447775-Genotype,
pubmed-meshheading:20447775-Haemophilus Infections,
pubmed-meshheading:20447775-Haemophilus parasuis,
pubmed-meshheading:20447775-Immunity, Maternally-Acquired,
pubmed-meshheading:20447775-Polymerase Chain Reaction,
pubmed-meshheading:20447775-Respiratory Tract Diseases,
pubmed-meshheading:20447775-Swine,
pubmed-meshheading:20447775-Swine Diseases,
pubmed-meshheading:20447775-Vaccination
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pubmed:year |
2010
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pubmed:articleTitle |
Sow vaccination modulates the colonization of piglets by Haemophilus parasuis.
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pubmed:affiliation |
Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus Univ. Autònoma de Barcelona, Bellaterra, Barcelona, Spain. marta.cerda@cresa.uab.cat
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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