Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19
pubmed:dateCreated
2010-5-7
pubmed:abstractText
Valvular heart disease, particularly aortic stenosis and mitral regurgitation, accounts for a large proportion of cardiology practice, and their prevalence is predicted to increase. Management of the asymptomatic patient remains controversial. Biomarkers have been shown to have utility in the management of cardiovascular disease such as heart failure and acute coronary syndromes. In this state-of-the-art review, we examine the current evidence relating to natriuretic peptides as potential biomarkers in aortic stenosis and mitral regurgitation. The natriuretic peptides correlate with measures of disease severity and symptomatic status and also can be used to predict outcome. This review shows that natriuretic peptides have much promise as biomarkers in common valvular heart disease, but the impact of their measurement on clinical practice and outcomes needs to be further assessed in prospective studies before routine clinical use becomes a reality.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1558-3597
pubmed:author
pubmed:copyrightInfo
Copyright 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
11
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2034-48
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Natriuretic peptides in common valvular heart disease.
pubmed:affiliation
Department of Cardiovascular Sciences, University Hospitals of Leicester, Leicester, UK. cds18@le.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't