Source:http://linkedlifedata.com/resource/pubmed/id/20435329
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2010-5-24
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pubmed:abstractText |
We explored the timescale, spatial spread, and risk group population structure of HIV-1 subtype B', the cause of explosive blood-borne HIV-1 epidemics among injecting drug users (IDUs) and former plasma donors (FPDs) in Asia. Sequences from FPDs in China formed a distinct monophyletic cluster within subtype B'. Further analysis revealed that subtype B' was founded by a single lineage of pandemic subtype B around 1985. Subsequently, the FPD cluster appears to have derived from a single subtype B' lineage around 1991, corroborating the hypothesis that FPD outbreaks stemmed from the preceding epidemic among IDUs in Southeast Asia, most likely from the Golden-Triangle region.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1096-0341
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
5
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pubmed:volume |
402
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
223-7
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pubmed:dateRevised |
2010-8-10
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pubmed:meshHeading |
pubmed-meshheading:20435329-Asia,
pubmed-meshheading:20435329-Blood Donors,
pubmed-meshheading:20435329-Cluster Analysis,
pubmed-meshheading:20435329-Genotype,
pubmed-meshheading:20435329-Geography,
pubmed-meshheading:20435329-HIV Infections,
pubmed-meshheading:20435329-HIV-1,
pubmed-meshheading:20435329-Humans,
pubmed-meshheading:20435329-Molecular Epidemiology,
pubmed-meshheading:20435329-RNA, Viral,
pubmed-meshheading:20435329-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20435329-Risk Factors,
pubmed-meshheading:20435329-Risk-Taking,
pubmed-meshheading:20435329-Sequence Analysis, DNA,
pubmed-meshheading:20435329-Sequence Homology,
pubmed-meshheading:20435329-Substance Abuse, Intravenous,
pubmed-meshheading:20435329-gag Gene Products, Human Immunodeficiency Virus
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pubmed:year |
2010
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pubmed:articleTitle |
Explosive HIV-1 subtype B' epidemics in Asia driven by geographic and risk group founder events.
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pubmed:affiliation |
Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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