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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-4-29
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pubmed:abstractText |
Twenty-eight Klebsiella pneumoniae clinical isolates that exhibited an extended-spectrum cephalosporin-resistance profile from a city in the Northeast of Brazil were analysed by PCR and DNA sequencing in order to determine the occurrence of blaCTX-M genes and class 1 integrons. We determined the occurrence of the blaCTX-M-2 gene in six K. pneumoniae isolates and describe the first detection of the blaCTX-M-28 gene in South America. Seven isolates carried class 1 integrons. Partial sequencing analysis of the 5'-3'CS variable region in the class 1 integrons of three isolates revealed the presence of aadA1, blaOXA-2 and dfr22 gene cassettes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1678-8060
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
163-7
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pubmed:meshHeading |
pubmed-meshheading:20428675-Anti-Bacterial Agents,
pubmed-meshheading:20428675-Base Sequence,
pubmed-meshheading:20428675-Brazil,
pubmed-meshheading:20428675-DNA, Bacterial,
pubmed-meshheading:20428675-Drug Resistance, Bacterial,
pubmed-meshheading:20428675-Humans,
pubmed-meshheading:20428675-Integrons,
pubmed-meshheading:20428675-Klebsiella pneumoniae,
pubmed-meshheading:20428675-Molecular Sequence Data,
pubmed-meshheading:20428675-Polymerase Chain Reaction,
pubmed-meshheading:20428675-Sequence Analysis, DNA,
pubmed-meshheading:20428675-beta-Lactamases
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pubmed:year |
2010
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pubmed:articleTitle |
bla(CTX-M-2) and bla(CTX-M-28) extended-spectrum beta-lactamase genes and class 1 integrons in clinical isolates of Klebsiella pneumoniae from Brazil.
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pubmed:affiliation |
Laboratório de Imunopatologia Keizo Asami, Universidade Federal de Pernambuco, Recife, PE, Brasil. ana.lopes.ufpe@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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