Linked Life Data

20427819

Source:http://linkedlifedata.com/resource/pubmed/id/20427819

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
29
pubmed:dateCreated
2010-4-29
pubmed:abstractText
The leading cause of death in cystic fibrosis (CF) patients is lung disease; yet despite enormous research efforts, its pathogenesis is not well understood. Because CF mice do not develop human-like airway disease, CF pigs were produced on the premise that they would offer insights into the pathogenesis of CF lung disease. But CF pigs develop severe intestinal blockage and often die shortly after birth. Now, a team of scientists report results from five CF pigs that lived for ~2 to 6 months; during this time, they developed some of the key features of human CF lung disease and revealed that infection precedes inflammation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1946-6242
pubmed:author
pubmed:issnType
Electronic
pubmed:day
28
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29ps20
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The development of lung disease in cystic fibrosis pigs.
pubmed:affiliation
Cystic Fibrosis Research Laboratory, Stanford University, Stanford, CA 94305-2130, USA. wine@stanford.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural