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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-7-1
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pubmed:abstractText |
Fibroblast growth factor 21 (FGF21) is a key metabolic regulator that is induced by peroxisome proliferator-activated receptor alpha (PPARalpha) activation in response to fasting. We recently reported that bezafibrate, a pan-agonist of PPARs, decreases body temperature late at night through hypothalamic neuropeptide Y (NPY) activation and others have shown that mice overexpressing FGF21 are prone to torpor.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0172-780X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
198-202
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pubmed:meshHeading |
pubmed-meshheading:20424589-Animals,
pubmed-meshheading:20424589-Body Temperature,
pubmed-meshheading:20424589-Fasting,
pubmed-meshheading:20424589-Fibroblast Growth Factors,
pubmed-meshheading:20424589-Hypothalamus,
pubmed-meshheading:20424589-Hypothermia,
pubmed-meshheading:20424589-Ketogenic Diet,
pubmed-meshheading:20424589-Liver,
pubmed-meshheading:20424589-Male,
pubmed-meshheading:20424589-Mice,
pubmed-meshheading:20424589-Mice, Inbred C57BL,
pubmed-meshheading:20424589-Mice, Knockout,
pubmed-meshheading:20424589-Motor Activity,
pubmed-meshheading:20424589-Neuropeptide Y,
pubmed-meshheading:20424589-RNA, Messenger,
pubmed-meshheading:20424589-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2010
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pubmed:articleTitle |
FGF21 is dispensable for hypothermia induced by fasting in mice.
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pubmed:affiliation |
Clock Cell Biology Research Group, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan. k-ooishi@aist.go.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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