Source:http://linkedlifedata.com/resource/pubmed/id/20420425
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2010-5-14
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pubmed:abstractText |
A robust, reproducible, and scalable method for the solid-phase synthesis of 5'-triphosphates of DNA, RNA, and their chemically modified analogues using 5'-H-phosphonate intermediates is described. 5'-Triphosphates of oligonucleotides with varying lengths and sequences containing different 5'-terminal nucleotides, with and without internal sugar-backbone modifications, were efficiently prepared as crude products or further purified by HPLC.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1523-7052
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
21
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2190-3
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
Efficient solid-phase chemical synthesis of 5'-triphosphates of DNA, RNA, and their analogues.
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pubmed:affiliation |
Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS, Université Montpellier 1 - Université Montpellier 2, Place Eugene Bataillon, CC1704, 34095 Montpellier Cedex 5, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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