20418343

Source:http://linkedlifedata.com/resource/pubmed/id/20418343

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0016390, umls-concept:C0547047, umls-concept:C1423062, umls-concept:C1522492, umls-concept:C1563937
pubmed:issue	18
pubmed:dateCreated	2010-9-15
pubmed:abstractText	Endothelial activation, macrophage infiltration, and foam cell formation are pivotal steps in atherogenesis. Our aim in this study was to analyse the role of SIRT1, a class III deacetylase with important metabolic functions, in plaque macrophages and atherogenesis.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8006263
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL, http://linkedlifedata.com/resource/pubmed/chemical/OLR1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/SIRT1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class E, http://linkedlifedata.com/resource/pubmed/chemical/Sirtuin 1, http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	1522-9645
pubmed:author	pubmed-author:BecherBurkhardB, pubmed-author:BeslerChristianC, pubmed-author:BorénJanJ, pubmed-author:HofmannJaninJ, pubmed-author:HottigerMichael OMO, pubmed-author:LüscherThomas FTF, pubmed-author:LandmesserUlfU, pubmed-author:LohmannChristineC, pubmed-author:MatterChristian MCM, pubmed-author:McBurneyMichael WMW, pubmed-author:RohrerLuciaL, pubmed-author:RothgiesserKarin MKM, pubmed-author:SchäferNicolaN, pubmed-author:SteinSokratesS
pubmed:issnType	Electronic
pubmed:volume	31
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2301-9
pubmed:meshHeading	pubmed-meshheading:20418343-Animals, pubmed-meshheading:20418343-Atherosclerosis, pubmed-meshheading:20418343-Bone Marrow Transplantation, pubmed-meshheading:20418343-Cell Differentiation, pubmed-meshheading:20418343-Cells, Cultured, pubmed-meshheading:20418343-Cholesterol, pubmed-meshheading:20418343-Foam Cells, pubmed-meshheading:20418343-Gene Deletion, pubmed-meshheading:20418343-Hypercholesterolemia, pubmed-meshheading:20418343-Lipoproteins, pubmed-meshheading:20418343-Lipoproteins, LDL, pubmed-meshheading:20418343-Macrophages, Peritoneal, pubmed-meshheading:20418343-Male, pubmed-meshheading:20418343-Mice, pubmed-meshheading:20418343-Mice, Inbred C57BL, pubmed-meshheading:20418343-Mice, Knockout, pubmed-meshheading:20418343-Scavenger Receptors, Class E, pubmed-meshheading:20418343-Sirtuin 1
pubmed:year	2010
pubmed:articleTitle	SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis.
pubmed:affiliation	Cardiovascular Research, Institute of Physiology, Zurich University and Cardiology, Cardiovascular Center, University Hospital Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't