Linked Life Data

20418150

Source:http://linkedlifedata.com/resource/pubmed/id/20418150

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-8-5
pubmed:abstractText
The endogenous circadian clock modulates cognitive performance over the daily 24-h cycle. Environmental disturbance of the clock, such as shift work or jet lag schedules, compromises sleep, alertness and problem solving. What is not generally appreciated, however, is that the circadian clock also modulates cognitive activity independently of time spent awake. The molecular identification of circadian clock genes in higher eukaryotes has revealed a conserved intracellular mechanism that, if disrupted by mutation, can have significant implications for mental and physical health. These molecular clocks tick away in different brain areas, and their circadian phases and anatomical relationships to the central brain pacemakers indicate new ways for understanding the mechanisms of interaction between circadian clocks, sleep and cognition.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1879-307X
pubmed:author
pubmed:copyrightInfo
(c) 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
259-67
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Circadian clocks: genes, sleep, and cognition.
pubmed:affiliation
Department of Genetics, University of Leicester, Leicester LE1 7RH, UK. cpk@leicester.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't