Source:http://linkedlifedata.com/resource/pubmed/id/20417992
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2010-10-29
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pubmed:abstractText |
The intracellular penetration and activity of UB-8902 in human polymorphonuclear leukocytes was evaluated. Intracellular UB-8902 concentrations were 6-fold higher than extracellular levels. Uptake was rapid, reversible, saturable, and affected by external pH. UB-8902 showed intracellular activity against Staphylococcus aureus strains presenting mutations associated with fluoroquinolone resistance in the gyrA and/or grlA genes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1578-1852
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2009 Elsevier España, S.L. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
612-4
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
Intracellular penetration and activity of UB-8902 in human polymorphonuclear leukocytes.
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pubmed:affiliation |
Departmento de Microbiología, Facultad de Medicina, Universidad de Sevilla, Seville, Spain. mudarra@us.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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