Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2010-10-29
pubmed:abstractText
The intracellular penetration and activity of UB-8902 in human polymorphonuclear leukocytes was evaluated. Intracellular UB-8902 concentrations were 6-fold higher than extracellular levels. Uptake was rapid, reversible, saturable, and affected by external pH. UB-8902 showed intracellular activity against Staphylococcus aureus strains presenting mutations associated with fluoroquinolone resistance in the gyrA and/or grlA genes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1578-1852
pubmed:author
pubmed:copyrightInfo
Copyright © 2009 Elsevier España, S.L. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
612-4
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Intracellular penetration and activity of UB-8902 in human polymorphonuclear leukocytes.
pubmed:affiliation
Departmento de Microbiología, Facultad de Medicina, Universidad de Sevilla, Seville, Spain. mudarra@us.es
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't