Source:http://linkedlifedata.com/resource/pubmed/id/20417415
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-4-26
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pubmed:abstractText |
Children with sickle-cell disease are at great risk of serious infections and early mortality. Our Review investigates the association between sickle-cell disease and invasive bacterial disease among populations in Africa. We systematically searched published work extracted data on pneumonia, meningitis, and bacteraemia by sickle-cell disease status. Most studies identified lacked a control group and did not use best laboratory methods for culturing fastidious bacteria. Only seven case-control or case-cohort studies provided data on the association between invasive bacterial disease and sickle-cell disease status. For all-cause laboratory-confirmed invasive bacterial disease, the pooled odds of sickle-cell disease was 19-times greater among cases than controls. For disease caused by Streptococcus pneumoniae, the pooled odds of sickle-cell disease was 36-times greater; and for Haemophilus influenzae type b disease it was 13-times greater.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1474-4457
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
329-37
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pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:20417415-Africa,
pubmed-meshheading:20417415-Anemia, Sickle Cell,
pubmed-meshheading:20417415-Animals,
pubmed-meshheading:20417415-Bacteremia,
pubmed-meshheading:20417415-Bacterial Infections,
pubmed-meshheading:20417415-Child, Preschool,
pubmed-meshheading:20417415-Humans,
pubmed-meshheading:20417415-Infant,
pubmed-meshheading:20417415-Meningitis, Bacterial,
pubmed-meshheading:20417415-Pneumonia,
pubmed-meshheading:20417415-Risk Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis.
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pubmed:affiliation |
meenaramakri@gmail.com
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Meta-Analysis
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