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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-4-26
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pubmed:abstractText |
A number of studies demonstrate that the polymorphisms in the 5 region of HTR2C play a pivotal role in antipsychotic drug efficacy. Since risperidone is an antagonist of HTR2C, polymorphic variations in HTR2C may explain variability in response to risperidone treatment. We analyzed HTR2C polymorphisms for association with efficacy of risperidone monotherapy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1744-8042
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pubmed:author |
pubmed-author:FengGuo-YinGY,
pubmed-author:HeGuangG,
pubmed-author:HeLinL,
pubmed-author:LiXing-WangXW,
pubmed-author:LiuBao-ChengBC,
pubmed-author:MauDD,
pubmed-author:WanChun-LingCL,
pubmed-author:WangLeiL,
pubmed-author:WangYangY,
pubmed-author:WeiZhi-YunZY,
pubmed-author:XuYi-FengYF,
pubmed-author:YangFeng-PingFP,
pubmed-author:ZhangJingJ
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
685-92
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pubmed:meshHeading |
pubmed-meshheading:20415561-Adult,
pubmed-meshheading:20415561-Antipsychotic Agents,
pubmed-meshheading:20415561-Asian Continental Ancestry Group,
pubmed-meshheading:20415561-Brief Psychiatric Rating Scale,
pubmed-meshheading:20415561-Female,
pubmed-meshheading:20415561-Gene Deletion,
pubmed-meshheading:20415561-Genotype,
pubmed-meshheading:20415561-Humans,
pubmed-meshheading:20415561-Linkage Disequilibrium,
pubmed-meshheading:20415561-Middle Aged,
pubmed-meshheading:20415561-Polymorphism, Genetic,
pubmed-meshheading:20415561-Polymorphism, Single Nucleotide,
pubmed-meshheading:20415561-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:20415561-Risperidone
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pubmed:year |
2010
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pubmed:articleTitle |
HTR2C promoter polymorphisms are associated with risperidone efficacy in Chinese female patients.
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pubmed:affiliation |
Bio-X Center, Key Laboratory for the Genetics of Developmental & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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