Source:http://linkedlifedata.com/resource/pubmed/id/20414862
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
15
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pubmed:dateCreated |
2010-10-25
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pubmed:abstractText |
Two new compounds, an isoflavone (1, 6-methoxybarbigerone) and a bipterocarpan (2, pachylobin) were isolated from the grains of Millettia pachyloba (Leguminosae), together with seven known compounds, 5-methoxybarbigerone (3), calopogoniumisoflavone B (4), durmillone (5), jamaicin (6), ichthynone (7), (-)-pisatin (8) and (-)-rotenone (9). The structures were established from spectroscopic analyses, including mass spectrometry and 2D-NMR. Absolute configuration of 2 was proposed based on that of the known compound (-)-pisatine (8). Compounds 1 and 2 exhibited cytotoxicity against KB cells with IC(50) values of 2.0 and 17.6?µM, respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1439-0221
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pubmed:author | |
pubmed:copyrightInfo |
© Georg Thieme Verlag KG Stuttgart · New York.
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pubmed:issnType |
Electronic
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1739-42
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pubmed:meshHeading |
pubmed-meshheading:20414862-Cytotoxins,
pubmed-meshheading:20414862-Humans,
pubmed-meshheading:20414862-Isoflavones,
pubmed-meshheading:20414862-KB Cells,
pubmed-meshheading:20414862-Millettia,
pubmed-meshheading:20414862-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:20414862-Prenylation,
pubmed-meshheading:20414862-Pterocarpans
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pubmed:year |
2010
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pubmed:articleTitle |
Cytotoxic prenylated isoflavone and bipterocarpan from Millettia pachyloba.
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pubmed:affiliation |
Institute of Chemistry-VAST, Hanoi, Vietnam. dtmhuong@ich.vast.ac.vn
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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