Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-7-15
pubmed:abstractText
6-Mercaptopurine (6-MP), the active metabolite of the immunosuppressive prodrug azathioprine, is commonly used in autoimmune diseases and transplant recipients, who are at high risk for cardiovascular disease. Here, we aimed to gain knowledge on the action of 6-MP in atherosclerosis, with a focus on monocytes and macrophages.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1524-4636
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1591-7
pubmed:meshHeading
pubmed-meshheading:20413732-6-Mercaptopurine, pubmed-meshheading:20413732-Animals, pubmed-meshheading:20413732-Antigens, CD31, pubmed-meshheading:20413732-Apolipoprotein E3, pubmed-meshheading:20413732-Apoptosis, pubmed-meshheading:20413732-Atherosclerosis, pubmed-meshheading:20413732-Cell Adhesion, pubmed-meshheading:20413732-Cells, Cultured, pubmed-meshheading:20413732-Chemokine CCL2, pubmed-meshheading:20413732-Chemotaxis, pubmed-meshheading:20413732-Disease Models, Animal, pubmed-meshheading:20413732-Dose-Response Relationship, Drug, pubmed-meshheading:20413732-Humans, pubmed-meshheading:20413732-Immunosuppressive Agents, pubmed-meshheading:20413732-Inflammation Mediators, pubmed-meshheading:20413732-Integrin alpha4beta1, pubmed-meshheading:20413732-Macrophages, pubmed-meshheading:20413732-Male, pubmed-meshheading:20413732-Mice, pubmed-meshheading:20413732-Mice, Inbred C57BL, pubmed-meshheading:20413732-Mice, Transgenic, pubmed-meshheading:20413732-Monocytes, pubmed-meshheading:20413732-Proto-Oncogene Proteins c-bcl-2, pubmed-meshheading:20413732-Time Factors, pubmed-meshheading:20413732-bcl-X Protein
pubmed:year
2010
pubmed:articleTitle
6-mercaptopurine inhibits atherosclerosis in apolipoprotein e*3-leiden transgenic mice through atheroprotective actions on monocytes and macrophages.
pubmed:affiliation
Department of Medical Biochemistry, Academic Medical Center, Amsterdam, the Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't