rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2010-5-20
|
pubmed:abstractText |
Survivors of childhood acute lymphoblastic leukemia (ALL) are at an increased risk of developing secondary malignant neoplasms. Radiation and chemotherapy can cause mutations and cytogenetic abnormalities and induce genomic instability. Host immunity and appropriate DNA damage responses are critical inhibitors of carcinogenesis. Therefore, we sought to determine the long-term effects of ALL treatment on immune function and response to DNA damage.
|
pubmed:grant |
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-10406363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-10607724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-10764140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-10973325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-11117911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-11567106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-11743585,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-11905813,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-11986221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-12663727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-12917300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-12960966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-14688377,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-14762065,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-14993208,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-15231655,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-15549093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-15734682,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-15879158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-15920008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-15995699,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-16258093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-16337364,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-16407512,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-16498454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-16807291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-16877676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-16888619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-16914325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-18084281,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-1922234,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-1997853,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-2072138,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-2501681,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-2787477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-2880018,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-3466000,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-4624721,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-6955009,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-7753173,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-7913156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-7933424,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-8672508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-8881368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-9476674,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-9718381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20413363-9838123
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1877-783X
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier Ltd. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
34
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
303-8
|
pubmed:dateRevised |
2011-7-28
|
pubmed:meshHeading |
pubmed-meshheading:20413363-Adolescent,
pubmed-meshheading:20413363-Adult,
pubmed-meshheading:20413363-Child,
pubmed-meshheading:20413363-DNA Damage,
pubmed-meshheading:20413363-Gene Expression,
pubmed-meshheading:20413363-Humans,
pubmed-meshheading:20413363-Immunity, Innate,
pubmed-meshheading:20413363-Lymphopenia,
pubmed-meshheading:20413363-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:20413363-Survivors,
pubmed-meshheading:20413363-T-Lymphocytes,
pubmed-meshheading:20413363-Thymus Gland,
pubmed-meshheading:20413363-Time,
pubmed-meshheading:20413363-Young Adult
|
pubmed:year |
2010
|
pubmed:articleTitle |
Deficient innate immunity, thymopoiesis, and gene expression response to radiation in survivors of childhood acute lymphoblastic leukemia.
|
pubmed:affiliation |
Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-2794, USA. wing.leung@stjude.org
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|