rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2010-10-12
|
pubmed:abstractText |
Around 300 million people world-wide suffer from asthma, and the prevalence of allergic diseases has increased. Much effort has been used in the study of mechanisms involved in the immune response observed in asthma to intervene for the treatment of this condition. During inflammation in asthma, Th2 cytokines and eosinophils are essential components of the host immune system. Furthermore, for therapeutic interventions against this disease, IL-10 is an important cytokine because it has a central role in the regulation of inflammatory cascades.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1365-2222
|
pubmed:author |
|
pubmed:copyrightInfo |
© 2010 Blackwell Publishing Ltd.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
40
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1541-51
|
pubmed:meshHeading |
pubmed-meshheading:20412136-Administration, Intranasal,
pubmed-meshheading:20412136-Animals,
pubmed-meshheading:20412136-Asthma,
pubmed-meshheading:20412136-Cell Separation,
pubmed-meshheading:20412136-Cytokines,
pubmed-meshheading:20412136-Disease Models, Animal,
pubmed-meshheading:20412136-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20412136-Female,
pubmed-meshheading:20412136-Flow Cytometry,
pubmed-meshheading:20412136-Gene Therapy,
pubmed-meshheading:20412136-Genetic Vectors,
pubmed-meshheading:20412136-Hypersensitivity,
pubmed-meshheading:20412136-Immunoglobulin E,
pubmed-meshheading:20412136-Immunoglobulin G,
pubmed-meshheading:20412136-Immunotherapy,
pubmed-meshheading:20412136-Interleukin-10,
pubmed-meshheading:20412136-Lactococcus lactis,
pubmed-meshheading:20412136-Lung,
pubmed-meshheading:20412136-Mice,
pubmed-meshheading:20412136-Mice, Inbred BALB C,
pubmed-meshheading:20412136-Ovalbumin,
pubmed-meshheading:20412136-Pneumonia,
pubmed-meshheading:20412136-Recombinant Proteins,
pubmed-meshheading:20412136-Th2 Cells
|
pubmed:year |
2010
|
pubmed:articleTitle |
An intranasal administration of Lactococcus lactis strains expressing recombinant interleukin-10 modulates acute allergic airway inflammation in a murine model.
|
pubmed:affiliation |
Department of Biochemistry and Immunology, Biological Sciences Institute, Federal University of Minas Gerais Minas Gerais, Belo Horizonte, MG, Brazil.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|