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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-4-20
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pubmed:databankReference |
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pubmed:abstractText |
The risk of severe adverse events following treatment of onchocerciasis with ivermectin in areas co-endemic with loiasis currently compromises the development of control programmes and the treatment of co-infected individuals. We therefore assessed whether doxycycline treatment could be used without subsequent ivermectin administration to effectively deliver sustained effects on Onchocerca volvulus microfilaridermia and adult viability. Furthermore we assessed the safety of doxycycline treatment prior to ivermectin administration in a subset of onchocerciasis individuals co-infected with low to moderate intensities of Loa loa microfilaraemia.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-10770311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-11356444,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-11741630,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-11920298,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-12133654,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-12537632,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-12706439,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-15119969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-15228717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-15287587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-15306713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-15363940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-15708387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-15964448,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-17002504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-17531279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-17574093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-17989786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-17999080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-18538871,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-18718154,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-18850111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-18978537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-19154624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-19621091,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-19712455,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-3291074,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-3548811,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-7002073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-8515109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20405054-8911442
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1935-2735
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pubmed:author |
pubmed-author:EnyongPeterP,
pubmed-author:EsumMathiasM,
pubmed-author:FaragherBrianB,
pubmed-author:FordLouiseL,
pubmed-author:HoeraufAchimA,
pubmed-author:JohnstonKelly LKL,
pubmed-author:LangleyR StuartRS,
pubmed-author:MandSabineS,
pubmed-author:SpechtSabineS,
pubmed-author:TaylorMark JMJ,
pubmed-author:TendongforNicholasN,
pubmed-author:TurnerJoseph DJD,
pubmed-author:WanjiSamuelS
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e660
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pubmed:dateRevised |
2010-9-30
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pubmed:meshHeading |
pubmed-meshheading:20405054-Adolescent,
pubmed-meshheading:20405054-Adult,
pubmed-meshheading:20405054-Animals,
pubmed-meshheading:20405054-Double-Blind Method,
pubmed-meshheading:20405054-Doxycycline,
pubmed-meshheading:20405054-Endemic Diseases,
pubmed-meshheading:20405054-Female,
pubmed-meshheading:20405054-Filaricides,
pubmed-meshheading:20405054-Humans,
pubmed-meshheading:20405054-Ivermectin,
pubmed-meshheading:20405054-Loiasis,
pubmed-meshheading:20405054-Male,
pubmed-meshheading:20405054-Middle Aged,
pubmed-meshheading:20405054-Onchocerca volvulus,
pubmed-meshheading:20405054-Onchocerciasis,
pubmed-meshheading:20405054-Placebos,
pubmed-meshheading:20405054-Treatment Outcome,
pubmed-meshheading:20405054-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.
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pubmed:affiliation |
Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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