Linked Life Data

20399755

Source:http://linkedlifedata.com/resource/pubmed/id/20399755

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-8-23
pubmed:abstractText
Leptin is well known as an important hormone in the central control of feeding behavior. During development, fetuses and newborns are exposed to leptin and recent evidence has shown that leptin receptors are widespread throughout the developing brain. Accordingly, leptin affects brain development during both pre- and postnatal life. The actions of leptin in the developing brain are generally permanent and range from the establishment of hypothalamic circuits to plasticity in cortical pathways. The cellular events mediated by leptin include the following: neurogenesis, axon growth, and synaptogenesis. Nutritional manipulation of leptin secretion during perinatal life has generated considerable concern, and the developing brain appears to be a particularly sensitive target for these environmental changes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1872-6240
pubmed:author
pubmed:copyrightInfo
2010 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
2
pubmed:volume
1350
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Neurodevelopmental actions of leptin.
pubmed:affiliation
The Saban Research Institute, Neuroscience Program, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA 90027, USA. sbouret@chla.usc.edu
pubmed:publicationType
Journal Article, Review