| pubmed-article:20398323 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20398323 | lifeskim:mentions | umls-concept:C0039597 | lld:lifeskim |
| pubmed-article:20398323 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:20398323 | lifeskim:mentions | umls-concept:C0449438 | lld:lifeskim |
| pubmed-article:20398323 | lifeskim:mentions | umls-concept:C0205618 | lld:lifeskim |
| pubmed-article:20398323 | lifeskim:mentions | umls-concept:C0013138 | lld:lifeskim |
| pubmed-article:20398323 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:20398323 | pubmed:dateCreated | 2010-6-15 | lld:pubmed |
| pubmed-article:20398323 | pubmed:abstractText | Increasing evidence demonstrates that stem cells maintain their identities by a unique transcription network and chromatin structure. Opposing epigenetic modifications H3K27 me3 and H3K4 me3 have been proposed to label differentiation-associated genes in stem cells, progenitor and precursor cells. In addition, many differentiation-associated genes are maintained at a poised status by recruitment of the initiative RNA Polymerase II (Pol II) at their promoter regions, in preparation for lineage-specific expression upon differentiation. Previous studies have been performed using cultured mammalian embryonic stem cells. To a lesser extent, chromatin structure has been delineated in other model organisms, such as Drosophila, to open new avenues for genetic analyses. | lld:pubmed |
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| pubmed-article:20398323 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20398323 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20398323 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:20398323 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20398323 | pubmed:issn | 1465-6914 | lld:pubmed |
| pubmed-article:20398323 | pubmed:author | pubmed-author:WeiGangG | lld:pubmed |
| pubmed-article:20398323 | pubmed:author | pubmed-author:ChenXinX | lld:pubmed |
| pubmed-article:20398323 | pubmed:author | pubmed-author:ZhaoKejiK | lld:pubmed |
| pubmed-article:20398323 | pubmed:author | pubmed-author:CuiKairongK | lld:pubmed |
| pubmed-article:20398323 | pubmed:author | pubmed-author:SchonesDustin... | lld:pubmed |
| pubmed-article:20398323 | pubmed:author | pubmed-author:GanQiangQ | lld:pubmed |
| pubmed-article:20398323 | pubmed:author | pubmed-author:Ho EunSukS | lld:pubmed |
| pubmed-article:20398323 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20398323 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:20398323 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20398323 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20398323 | pubmed:pagination | R42 | lld:pubmed |
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