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pubmed-article:20396999pubmed:abstractTextOverexpression of PED (also known as PEA15) determines insulin resistance and impaired insulin secretion and may contribute to progression toward type 2 diabetes. Recently, we found that the transcription factor hepatocyte nuclear factor (HNF)-4alpha binds to PED promoter and represses its transcription. However, the molecular details responsible for regulation of PED gene remain unclear.lld:pubmed
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pubmed-article:20396999pubmed:articleTitleHepatocyte nuclear factor (HNF)-4alpha-driven epigenetic silencing of the human PED gene.lld:pubmed
pubmed-article:20396999pubmed:affiliationDipartimento di Biologia e Patologia Cellulare e Molecolare L. Califano & Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, Università di Napoli Federico II, Via Sergio Pansini, 5, Naples, 80131, Italy. pungaro@ieos.cnr.itlld:pubmed
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