| pubmed-article:20395150 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20395150 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:20395150 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:20395150 | lifeskim:mentions | umls-concept:C0243072 | lld:lifeskim |
| pubmed-article:20395150 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:20395150 | pubmed:dateCreated | 2010-4-30 | lld:pubmed |
| pubmed-article:20395150 | pubmed:abstractText | This paper reports the synthesis of new derivatives (formed by two indole systems separated by a central moiety) analogous of potent antitumor agents previously described. The activity of the bis-indoles bearing a pyridine core confirms the good result described in the previous paper and compound 4c was chosen for the first in vivo experiment (Hollow Fiber Assay). COMPARE analysis and structure-activity relationships were also considered. Contrary to data reported by other Authors, no correlations were found between antitumor activity and NQO1 induction. | lld:pubmed |
| pubmed-article:20395150 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20395150 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20395150 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20395150 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20395150 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20395150 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20395150 | pubmed:month | May | lld:pubmed |
| pubmed-article:20395150 | pubmed:issn | 1464-3391 | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:KimW GWG | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:ShoemakerRobe... | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:AndreaniAldoA | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:GranaiolaMass... | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:LeoniAlbertoA | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:LocatelliAles... | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:MorigiRitaR | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:RambaldiMirel... | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:VaroliLucilla... | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:BurnelliSilvi... | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:PrataCeciliaC | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:CalicetiCrist... | lld:pubmed |
| pubmed-article:20395150 | pubmed:author | pubmed-author:Dalla... | lld:pubmed |
| pubmed-article:20395150 | pubmed:copyrightInfo | (c) 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:20395150 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20395150 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:20395150 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:20395150 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20395150 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20395150 | pubmed:pagination | 3004-11 | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:meshHeading | pubmed-meshheading:20395150... | lld:pubmed |
| pubmed-article:20395150 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20395150 | pubmed:articleTitle | Antitumor activity and COMPARE analysis of bis-indole derivatives. | lld:pubmed |
| pubmed-article:20395150 | pubmed:affiliation | Dipartimento di Scienze Farmaceutiche, Università di Bologna, Via Belmeloro 6, 40126 Bologna, Italy. aldo.andreani@unibo.it | lld:pubmed |
| pubmed-article:20395150 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:20395150 | lld:chembl |
