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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
15
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pubmed:dateCreated |
2010-10-25
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pubmed:abstractText |
In the course of screening plants used in folk medicine as memory enhancers, a 70% ethanolic extract of Stephania rotunda roots showed significant AChE inhibitory activity. Repeated column chromatography led to the isolation of a new protoberberine alkaloid, which we named stepharotudine (1), and seven known compounds (2-8). The chemical structures of the isolated compounds were elucidated based on extensive 1D and 2D NMR spectroscopic data. Compounds 1-8 were investigated in vitro for their anticholinesterase activity using a rat cortex AChE enzyme.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1439-0221
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pubmed:author |
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pubmed:copyrightInfo |
© Georg Thieme Verlag KG Stuttgart · New York.
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pubmed:issnType |
Electronic
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1762-4
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pubmed:meshHeading |
|
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pubmed:year |
2010
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pubmed:articleTitle |
Alkaloids from roots of Stephania rotunda and their cholinesterase inhibitory activity.
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pubmed:affiliation |
College of Pharmacy, Catholic University of Daegu, Gyeongbuk, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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