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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0017337,
umls-concept:C0019196,
umls-concept:C0019682,
umls-concept:C0019699,
umls-concept:C0030705,
umls-concept:C0087111,
umls-concept:C0752046,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
8
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pubmed:dateCreated |
2010-4-27
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pubmed:abstractText |
Given that peginterferon-ribavirin treatment is poorly tolerated, there is interest in the identification of predictors of response, particularly in HIV/hepatitis C virus (HCV)-coinfected patients that respond less than HCV-monoinfected individuals. A single nucleotide polymorphism (SNP) near the IL28B gene (rs12979860) has been shown to predict treatment response in HCV-monoinfected patients carrying genotype 1. Information is lacking for HIV/HCV-coinfected individuals and/or other HCV genotypes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/IL28B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukins,
http://linkedlifedata.com/resource/pubmed/chemical/Polyethylene Glycols,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Ribavirin,
http://linkedlifedata.com/resource/pubmed/chemical/interferon alfa-2a,
http://linkedlifedata.com/resource/pubmed/chemical/peginterferon alfa-2a
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1473-5571
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pubmed:author |
pubmed-author:AlexThompsonT,
pubmed-author:BenitoJosé MJM,
pubmed-author:GoldsteinDavidD,
pubmed-author:McHutchisonJohnJ,
pubmed-author:MedranoJoséJ,
pubmed-author:NaggieSusannaS,
pubmed-author:RallónNorma INI,
pubmed-author:RestrepoClaraC,
pubmed-author:ShiannaKevin VKV,
pubmed-author:SorianoVincentV,
pubmed-author:VispoEugeniaE
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
F23-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20389235-Adult,
pubmed-meshheading:20389235-Drug Therapy, Combination,
pubmed-meshheading:20389235-Female,
pubmed-meshheading:20389235-Genotype,
pubmed-meshheading:20389235-HIV Infections,
pubmed-meshheading:20389235-Hepacivirus,
pubmed-meshheading:20389235-Hepatitis C,
pubmed-meshheading:20389235-Humans,
pubmed-meshheading:20389235-Interferon-alpha,
pubmed-meshheading:20389235-Interleukins,
pubmed-meshheading:20389235-Liver Cirrhosis,
pubmed-meshheading:20389235-Male,
pubmed-meshheading:20389235-Middle Aged,
pubmed-meshheading:20389235-Polyethylene Glycols,
pubmed-meshheading:20389235-Polymorphism, Single Nucleotide,
pubmed-meshheading:20389235-RNA, Viral,
pubmed-meshheading:20389235-Recombinant Proteins,
pubmed-meshheading:20389235-Ribavirin,
pubmed-meshheading:20389235-Risk Factors,
pubmed-meshheading:20389235-Spain,
pubmed-meshheading:20389235-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients.
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pubmed:affiliation |
Infectious Diseases Department, Hospital Carlos III, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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