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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-7-2
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pubmed:abstractText |
We examined the plasma-protein-binding of 67-gallium in 10 patients with probable dementia of the Alzheimer-type (DAT), diagnosed according to NINCDS-ADRDA-criteria, and in 10 healthy controls matched for age (mean: 82 and 83 years) and sex (2m:8f). In comparison to the control group, the percentage of 67-gallium bound in the plasma of DAT-patients was significantly decreased (10.6% vs 15.5%; p less than 0.05). As gallium and aluminum show corresponding biochemical characteristics, these results may indicate a potential contribution of a disturbed peripheral transport in DAT, leading to the intracerebral deposition of neurotoxic aluminum levels.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0044-281X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
24-6
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:2038885-Aged,
pubmed-meshheading:2038885-Aged, 80 and over,
pubmed-meshheading:2038885-Aluminum,
pubmed-meshheading:2038885-Alzheimer Disease,
pubmed-meshheading:2038885-Female,
pubmed-meshheading:2038885-Gallium Radioisotopes,
pubmed-meshheading:2038885-Humans,
pubmed-meshheading:2038885-Male,
pubmed-meshheading:2038885-Protein Binding,
pubmed-meshheading:2038885-Risk Factors
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pubmed:articleTitle |
[Decreased 67-gallium plasma protein binding in senile dementia of the Alzheimer type].
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pubmed:affiliation |
Section of Old Age, Institute of Psychiatry, London, United Kingdom.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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