Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-7-2
pubmed:abstractText
We examined the plasma-protein-binding of 67-gallium in 10 patients with probable dementia of the Alzheimer-type (DAT), diagnosed according to NINCDS-ADRDA-criteria, and in 10 healthy controls matched for age (mean: 82 and 83 years) and sex (2m:8f). In comparison to the control group, the percentage of 67-gallium bound in the plasma of DAT-patients was significantly decreased (10.6% vs 15.5%; p less than 0.05). As gallium and aluminum show corresponding biochemical characteristics, these results may indicate a potential contribution of a disturbed peripheral transport in DAT, leading to the intracerebral deposition of neurotoxic aluminum levels.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0044-281X
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
24-6
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:articleTitle
[Decreased 67-gallium plasma protein binding in senile dementia of the Alzheimer type].
pubmed:affiliation
Section of Old Age, Institute of Psychiatry, London, United Kingdom.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't