Linked Life Data

20386875

Source:http://linkedlifedata.com/resource/pubmed/id/20386875

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-7-23
pubmed:abstractText
While the familial form of Alzheimer's disease (AD) is known to be entirely inherited, the etiopathogenesis of the most common late-onset form of Alzheimer's disease still remains unresolved. Among various factors, aging seems to be one of the most prominent risk factors. Moreover, a large body of evidence points to the contribution of immunological alterations in AD. The involvement of inflammatory factors in the etiopathology has been widely discussed. Moreover, an impairment of certain immune responses in AD has been observed. Presumably, premature immunosenescence may lead to inadequate immune reactions. Against this background, the development of different immunotherapeutic strategies seems to be a promising challenge for future research.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1433-0407
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
837-43
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
[Premature immunosenescence: a pathogenetic factor in Alzheimer's disease?].
pubmed:affiliation
Universitätsklinik für Psychiatrie und Psychotherapie, Tübingen, Tübingen, Deutschland. elke.richartz@gmx.de
pubmed:publicationType
Journal Article, English Abstract, Review