Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-6-11
pubmed:abstractText
Transforming growth factor-beta1 (TGF-beta1) contributes to the pathogenesis of Peyronie's disease (PD). Pentoxifylline (PTX) antagonizes the effects of TGF-beta1 and has been utilized in our clinic for the management of PD although the mechanisms of action are not entirely clear.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-10329205, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-10692396, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-11252892, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-11804868, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-14521923, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-14745449, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-14996430, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-15715940, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-15987746, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-16110351, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-16782264, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-17027893, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-17209135, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-17581631, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-17727468, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-17950078, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-18228265, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-18679024, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-18694570, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-18794361, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-19473283, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-7052708, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-7861547, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-9043496, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-9302128, http://linkedlifedata.com/resource/pubmed/commentcorrection/20384945-9366377
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1743-6109
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1787-97
pubmed:dateRevised
2011-9-13
pubmed:meshHeading
pubmed-meshheading:20384945-Blotting, Western, pubmed-meshheading:20384945-Carrier Proteins, pubmed-meshheading:20384945-Collagen, pubmed-meshheading:20384945-Dose-Response Relationship, Drug, pubmed-meshheading:20384945-Down-Regulation, pubmed-meshheading:20384945-Elastic Tissue, pubmed-meshheading:20384945-Elastin, pubmed-meshheading:20384945-Fibroblasts, pubmed-meshheading:20384945-Gene Expression, pubmed-meshheading:20384945-Humans, pubmed-meshheading:20384945-Male, pubmed-meshheading:20384945-Penile Induration, pubmed-meshheading:20384945-Penis, pubmed-meshheading:20384945-Pentoxifylline, pubmed-meshheading:20384945-Phosphodiesterase Inhibitors, pubmed-meshheading:20384945-RNA, Messenger, pubmed-meshheading:20384945-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:20384945-Signal Transduction, pubmed-meshheading:20384945-Smad Proteins, pubmed-meshheading:20384945-Transforming Growth Factor beta1
pubmed:year
2010
pubmed:articleTitle
Pentoxifylline attenuates transforming growth factor-beta1-stimulated elastogenesis in human tunica albuginea-derived fibroblasts part 2: Interference in a TGF-beta1/Smad-dependent mechanism and downregulation of AAT1.
pubmed:affiliation
Knuppe Molecular Urology Laboratory, Department of Urology, University of California, San Francisco, CA 94143-0738, United States. glin@urology.ucsf.edu
pubmed:publicationType
Journal Article