Linked Life Data

20384410

Source:http://linkedlifedata.com/resource/pubmed/id/20384410

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-4-13
pubmed:abstractText
Intake of diets high in saturated fat and simple carbohydrates is associated with cognitive impairments in both humans and rodents. Here we report that feeding rats this type of high-energy (HE) diet has different effects on different types of learning and memory processes. Rats were first trained to solve spatial and nonspatial reference (RM) and working (WM) memory problems in a radial maze paradigm. Memory retention was assessed following six durations of free access to an HE or standard chow control diet ranging from 72-hr to 90 days. The results showed that performance on spatial RM and WM was impaired following only 72-hr on the HE diet and that the magnitude of the spatial RM and WM retention deficits were stable across all tests. On the other hand, stable deficits in nonspatial RM and WM emerged only after 30 days on the HE diet. The results suggest that the processes underlying spatial memory may be especially sensitive to disruption following intake of HE diets.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1939-2184
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
313-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Different patterns of memory impairments accompany short- and longer-term maintenance on a high-energy diet.
pubmed:affiliation
Department of Psychological Sciences and the Ingestive Behavior Research Center, West Lafayette, Indiana, USA. kanoski@sas.upenn.edu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural