Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-5-28
pubmed:abstractText
Bioassay-guided fractionation of the roots of Litsea hypophaea led to the isolation of seven new butanolides, namely, litseakolides H-N (1-7), all with the 3R,4S configuration, as well as three new biarylpropanoids, hypophaone (8), hypophaol (9), and hypophane (10), and 15 known compounds. The structures of 1-10 were determined by means of spectroscopic analysis. Litseakolide L (5) and N-trans-feruloylmethoxytyramine (11) showed antitubercular activity against Mycobacterium tuberculosis strain H(37)Rv, with MIC values of 25 and 1.6 microg/mL, respectively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1520-6025
pubmed:author
pubmed:issnType
Electronic
pubmed:day
28
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
890-6
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Secondary metabolites from the roots of Litsea hypophaea and their antitubercular activity.
pubmed:affiliation
Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan 807, Republic of China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't