rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-4-13
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pubmed:abstractText |
Materials advances enabled by nanotecbnology have brought about promising approaches to improve the encapsulation mechanism for immunoisolated cell-based drug delivery. Cell-based drug delivery is a promising treatment for many diseases but has thus far achieved only limited clinical success. Treatment of insulin dependent diabetes mellitus (IDDM) by transplantation of pancreatic beta-cells represents the most anticipated application ofcell-based drug delivery technology. This review outlines the challenges involved with maintaining transplanted cell viability and discusses how inorganic nanoporous membranes may be useful in achieving clinical success.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0065-2598
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
670
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
104-25
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20384222-Aluminum Oxide,
pubmed-meshheading:20384222-Animals,
pubmed-meshheading:20384222-Diabetes Mellitus, Type 1,
pubmed-meshheading:20384222-Drug Compounding,
pubmed-meshheading:20384222-Drug Delivery Systems,
pubmed-meshheading:20384222-Humans,
pubmed-meshheading:20384222-Immunosuppressive Agents,
pubmed-meshheading:20384222-Insulin,
pubmed-meshheading:20384222-Islets of Langerhans Transplantation,
pubmed-meshheading:20384222-Membranes, Artificial,
pubmed-meshheading:20384222-Nanostructures,
pubmed-meshheading:20384222-Porosity,
pubmed-meshheading:20384222-Silicon,
pubmed-meshheading:20384222-Titanium
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pubmed:year |
2010
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pubmed:articleTitle |
Inorganic nanoporous membranes for immunoisolated cell-based drug delivery.
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pubmed:affiliation |
UCSF/UCB Joint Graduate Group in Bioengineering, University of California, San Francisco, University of California, Berkeley, USA.
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pubmed:publicationType |
Journal Article,
Review
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