Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-4-12
pubmed:abstractText
The Atrial Fibrillation: Focus on Effective Clinical Treatment Strategies (AFFECTS) Registry was designed to examine atrial fibrillation (AF) treatment by United States cardiologists in the context of the American College of Cardiology, American Heart Association, and European Society of Cardiology guidelines after recent landmark clinical trials. Most patients in AFFECTS had AF without clinically significant structural heart disease or only uncomplicated hypertension. Among the all-enrolled population (n = 1,461), initial treatment strategies assigned were rhythm control in 64% and rate control in 36%. Among patients with either paroxysmal (n = 1,165) or persistent (n = 273) AF, 67% and 55%, respectively, were assigned rhythm control. The trend to assign rhythm control as the initial treatment goal decreased with age. In the rhythm-control group, most patients (74%) also received a rate-control agent during the registry, while 25% of those assigned to rate control received antiarrhythmic drugs. Most first prescriptions of antiarrhythmic drugs were for first-line therapy compliant with 2001 (76%) and 2006 (86%) guidelines. Most second prescriptions were for first-line therapies as well. Rates of serious adverse events were low. In conclusion, data from this study provide insight into community treatment patterns in patients with AF, most without clinically significant structural heart disease or with only uncomplicated hypertension.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1879-1913
pubmed:author
pubmed:copyrightInfo
Copyright 2010 Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
105
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1122-9
pubmed:meshHeading
pubmed-meshheading:20381664-Adolescent, pubmed-meshheading:20381664-Adult, pubmed-meshheading:20381664-Aged, pubmed-meshheading:20381664-Aged, 80 and over, pubmed-meshheading:20381664-Anti-Arrhythmia Agents, pubmed-meshheading:20381664-Atrial Fibrillation, pubmed-meshheading:20381664-Cardiology, pubmed-meshheading:20381664-Clinical Competence, pubmed-meshheading:20381664-Drug Prescriptions, pubmed-meshheading:20381664-Female, pubmed-meshheading:20381664-Follow-Up Studies, pubmed-meshheading:20381664-Heart Rate, pubmed-meshheading:20381664-Humans, pubmed-meshheading:20381664-Male, pubmed-meshheading:20381664-Middle Aged, pubmed-meshheading:20381664-Physician's Practice Patterns, pubmed-meshheading:20381664-Physicians, pubmed-meshheading:20381664-Practice Guidelines as Topic, pubmed-meshheading:20381664-Prospective Studies, pubmed-meshheading:20381664-Registries, pubmed-meshheading:20381664-Survival Rate, pubmed-meshheading:20381664-Treatment Outcome, pubmed-meshheading:20381664-United States, pubmed-meshheading:20381664-Young Adult
pubmed:year
2010
pubmed:articleTitle
Practice patterns among United States cardiologists for managing adults with atrial fibrillation (from the AFFECTS Registry).
pubmed:affiliation
Columbia University, New York, NY, USA. jar2@columbia.edu
pubmed:publicationType
Journal Article, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study