|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2010-5-28
|
|
pubmed:abstractText |
One-third of myocarditis cases progresses to dilated cardiomyopathy (DCM), but the mechanisms controlling this process are largely unknown. CD4(+) T helper (Th)17 cells have been implicated in the pathogenesis of autoimmune diseases, but the role of Th17-produced cytokines during inflammation-induced cardiac remodeling has not been previously studied.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1524-4571
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
28
|
|
pubmed:volume |
106
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1646-55
|
|
pubmed:meshHeading |
pubmed-meshheading:20378858-Animals,
pubmed-meshheading:20378858-Antigens, CD,
pubmed-meshheading:20378858-CD4-Positive T-Lymphocytes,
pubmed-meshheading:20378858-Cardiomyopathies,
pubmed-meshheading:20378858-Chemokines,
pubmed-meshheading:20378858-Cytokines,
pubmed-meshheading:20378858-Disease Models, Animal,
pubmed-meshheading:20378858-Disease Progression,
pubmed-meshheading:20378858-Flow Cytometry,
pubmed-meshheading:20378858-Immunization,
pubmed-meshheading:20378858-Inflammation,
pubmed-meshheading:20378858-Interleukin-17,
pubmed-meshheading:20378858-Male,
pubmed-meshheading:20378858-Mice,
pubmed-meshheading:20378858-Mice, Inbred BALB C,
pubmed-meshheading:20378858-Mice, Knockout,
pubmed-meshheading:20378858-Mice, Transgenic,
pubmed-meshheading:20378858-Myocarditis,
pubmed-meshheading:20378858-Ventricular Function, Left,
pubmed-meshheading:20378858-Ventricular Remodeling
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Interleukin-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy.
|
|
pubmed:affiliation |
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
