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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-5-3
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pubmed:databankReference |
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pubmed:abstractText |
Histone deacetylase (HDAC) inhibitors have shown radiosensitising activity in preclinical tumour models. This phase 1 study assessed the use of vorinostat combined with pelvic palliative radiotherapy for gastrointestinal carcinoma.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1474-5488
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pubmed:author |
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pubmed:copyrightInfo |
2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
459-64
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pubmed:meshHeading |
pubmed-meshheading:20378407-Aged,
pubmed-meshheading:20378407-Aged, 80 and over,
pubmed-meshheading:20378407-Colonic Neoplasms,
pubmed-meshheading:20378407-Combined Modality Therapy,
pubmed-meshheading:20378407-Dose-Response Relationship, Drug,
pubmed-meshheading:20378407-Dose-Response Relationship, Radiation,
pubmed-meshheading:20378407-Female,
pubmed-meshheading:20378407-Gastrointestinal Neoplasms,
pubmed-meshheading:20378407-Histone Deacetylase Inhibitors,
pubmed-meshheading:20378407-Humans,
pubmed-meshheading:20378407-Hydroxamic Acids,
pubmed-meshheading:20378407-Male,
pubmed-meshheading:20378407-Maximum Tolerated Dose,
pubmed-meshheading:20378407-Middle Aged,
pubmed-meshheading:20378407-Palliative Care,
pubmed-meshheading:20378407-Pelvic Neoplasms,
pubmed-meshheading:20378407-Rectal Neoplasms,
pubmed-meshheading:20378407-Stomach Neoplasms
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pubmed:year |
2010
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pubmed:articleTitle |
Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study.
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pubmed:affiliation |
Department of Tumour Biology, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway. a.h.ree@medisin.uio.no
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase I
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